Deliberately Infecting Healthy Volunteers with Malaria Parasites: Perceptions and Experiences of Participants and Other Stakeholders in a Kenyan‐Based Malaria Infection Study

Irene Jao, Vicki Marsh, Primus Che Chi, Melissa Kapulu, Mainga Hamaluba, Sassy Molyneux (University of Oxford), Philip Bejon, Dorcas Kamuya, Deliberately Infecting Healthy Volunteers with Malaria Parasites: Perceptions and Experiences of Participants and Other Stakeholders in a Kenyan‐Based Malaria Infection Study, 34(8) Bioethics 819 (2020):

Controlled human malaria infection (CHMI) studies involve the deliberate infection of healthy volunteers with malaria parasites under controlled conditions to study immune responses and/or test drug or vaccine efficacy. An empirical ethics study was embedded in a CHMI study at a Kenyan research programme to explore stakeholders’ perceptions and experiences of deliberate infection and moral implications of these.