On April 22, 2020, Alaska Governor Mike Dunleavy, Alaska Department of Health and Social Services Commissioner Adam Crum, and Dr. Anne Zink, Chief Medical Officer for the State of Alaska, issued Health Mandate 16 (effective April 24, 2020) to balance “the ongoing need to maintain diligent efforts to slow and disrupt the rate of infection with the corresponding critical need to resume economic activity in a reasonable and safe manner.” This approach reflects Alaska’s first phase in plans to reopen business activity in the state during the COVID-19 pandemic.